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KMID : 0812020060120010055
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Korean Journal of Neurogastroenterology and Motility
2006 Volume.12 No. 1 p.55 ~ p.62
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Factors associated with the Development of Paralytic Ileus in Medical ICU Patients on Mechanical Ventilation
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Song Ji-Hyun
Jung Sung-Ae
Kim Seong-Eun
Song Hyun-Joo
Oh Hee-Jung
Ryu Kum-Hei
Yeom Hye-Jung
Kim Tae-Hun
Shim Ki-Nam
Yoo Kwon
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Abstract
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Background/Aims: The aim of this study was to analyze the clinical characteristics of patients who develop paralytic ileus while on mechanical ventilation.
Methods: The medical records of 817 patients on mechanical ventilation from December 2001 to July 2004 were reviewed retrospectively. With the exception of ileus secondary to organic diseases, drugs and the diseases that affect bowel motility, 29 patients (14 in the ileus group and 15 in the control group) were enrolled. Clinical and laboratory findings on admission, at the time of starting ventilator treatment and at the time of the development of ileus were compared between the two groups.
Results: High fever was more common in the ileus group (p<0.05). The prevalence of hypoxemia and hypotension and the parameters of ventilatory settings were not different at the initiation of ventilator treatment. At the time of the development of ileus, the ileus group tended to have a higher leukocyte count (p=0.05), a significantly more prominent rise in the CRP level (p<0.01) and a higher mortality rate (p=0.14).
Conclusions: In patients on mechanical ventilation, the status of infection or inflammation appears to affect the development of ileus more significantly than the ventilatory settings. Control of underlying inflammatory conditions may be important to prevent ileus. (Kor J Neurogastroenterol Motil 2006;12:55-62)
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KEYWORD
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Paralytic ileus, Mechanical ventilation
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